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Scientific knowledge has greatly advanced since the 16th century.
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Vocabulary list

kagakuteki
na adjective
  1. scientific
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kagaku
noun
  1. science
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teki
suffix, na adjective
  1. -ical; -ive; -al; -ic; -y (used to form adjectives from nouns)
  2. -like; -ish; -sort of; -kind of
  3. (something) like; along the lines of (used similarly to a quoting particle, esp. as 的な or 的なこと)
  4. -wise; in terms of; for; from the viewpoint of; from a ... standpoint; as far as ... is concerned (after a noun or pronoun, esp. adverbially as ～に(は))
suffix
  1. Mr.; Ms.; Mrs. (used as a form of address with names, work titles, etc. to denote either light disdain or familiarity)
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chishiki
noun
  1. knowledge; information
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ha
particle
  1. topic marker particle (pronounced わ in modern Japanese)
  2. indicates contrast with another option (stated or unstated)
  3. adds emphasis
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juuroku
numeric
  1. 16; sixteen
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seiki
noun
  1. century
  2. era
no adjective
  1. of the century (e.g. fight of the century)
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irai
noun, adverb
  1. since; henceforth
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ooini
adverb
  1. very; much; greatly; a lot of
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shinpo
noun, suru verb
  1. progress; advance; improvement; development
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suru

te-form

shite
suru verb (irregular)
  1. to do; to carry out; to perform
  2. to cause to become; to make (into); to turn (into)
  3. to serve as; to act as; to work as
  4. to wear (clothes, a facial expression, etc.)
  5. to judge as being; to view as being; to think of as; to treat as; to use as (as 〜にする,〜とする)
  6. to decide on; to choose (as 〜にする)
suru verb (irregular), intransitive verb
  1. to be sensed (of a smell, noise, etc.) (as 〜がする)
  2. to be (in a state, condition, etc.)
  3. to be worth; to cost
  4. to pass (of time); to elapse
suru verb (irregular), transitive verb
  1. to place, or raise, person A to a post or status B (as AをBにする)
  2. to transform A to B; to make A into B; to exchange A for B (as AをBにする)
  3. to make use of A for B; to view A as B; to handle A as if it were B (as AをBにする)
  4. to feel A about B (as AをBにする)
suffix, suru verb (irregular)
  1. verbalizing suffix (applies to nouns noted in this dictionary with the part of speech "vs")
auxiliary verb, suru verb (irregular)
  1. creates a humble verb (after a noun prefixed with "o" or "go")
  2. to be just about to; to be just starting to; to try to; to attempt to (as 〜うとする,〜ようとする)
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Suffix after the te form of a verb
kuru

Plain Past Indicative Form

kita
kuru verb, intransitive verb, auxiliary verb
  1. to come back; to do ... and come back (after the -te form of a verb)
  2. to come to be; to become; to get; to grow; to continue (after the -te form of a verb)
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